How to Say "Take Care of Me" in Spanish

cuídame

/kwidame/from spelling rules

In Spanish, the phrase for "take care of me" is cuídame.

This phrase is used as a request for someone to look after your well-being or to keep you safe.

Which one should you use?

The form cuídame is a direct command or request. In contrast, me cuidas is used as a statement or a question depending on the speaker's intonation.

In Mexico, the phrase Cuídame, por favor. is used to say "Take care of me, please."

The form cuídame uses the informal tú imperative. If you are speaking to someone in a formal context, you would use cuídeme.

/kwidame/

In some Latin American contexts, saying cuídame to a friend when they are leaving is a warm way of saying 'look after yourself', even though the grammar literally asks the other person to take care of the speaker.
The word cuida is related to the Old Spanish word for 'thought' or 'concern'. Historically, taking care of someone meant keeping them in your thoughts.
Spanish has a specific verb, mimar, for a type of 'care' that means 'to pamper' or 'to spoil'. While cuídame asks for protection, mímame asks for affection and indulgence.

Cuídame.
Take care of me.
This example shows the direct command cuídame.
Tatoeba #2108712 by alexmarcelo, translation #7917594 by fpp
Cuídame, ¿sí?
Take care of me, okay?
Doctor, cuídeme durante mi recuperación, por favor.
Doctor, take care of me during my recovery, please.
Por favor, cuídame mientras estoy enfermo.
Please, take care of me while I am sick.

Mateo is feeling unwell and talking to Lucía.

Sources

IPA marked “from spelling rules” is derived from standard Spanish spelling, where Wiktionary gives none.
Example sentences: Tatoeba CC BY 2.0 FR.

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