What does it mean word for word?
The phrase ahora mismo means "right now".
Which one should you use?
While ¿estás hablando en serio ahora mismo, hermano? is a direct translation of the full English phrase, you can use other variations depending on the level of informality or the specific nuance you want to convey. ¿En serio? is the most concise version. You might also use ¿En serio ahora mismo, amigo? to say "Are you serious right now, friend?" or ¿De verdad lo dices, tío? to say "Are you really saying that, dude?"
Is there a formal and an informal way to say it?
The word hermano functions as an informal way to say "bro" or "man" when used at the end of a sentence. Consequently, the full phrase is informal. Similarly, using amigo (friend) or tío (dude) creates informal variations.
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Example conversation
Daniel tells María he forgot their dinner reservation.
- DanielOlvidé nuestra reserva para cenar.I forgot our dinner reservation.
- María¿Estás hablando en serio ahora mismo, hermano?Are you serious right now, bro?
- DanielLo siento mucho, María.I am very sorry, María.
- MaríaNo puedo creer que lo hicieras.I can't believe you did that.